Blar i forfatter "Díez-del-Molino, David"

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    • Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome 

      van der Valk, Tom; Dehasque, Marianne; Chacón-Duque, J. Camilo; Oskolkov, Nikolay; Vartanyan, Sergey; Heintzman, Peter D.; Pečnerová, Patrícia; Díez-del-Molino, David; Dalén, Love (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-01)
      Woolly mammoths had a set of adaptations that enabled them to thrive in the Arctic environment. Many mammoth-specific single nucleotide polymorphisms (SNPs) responsible for unique mammoth traits have been previously identified from ancient genomes. However, a multitude of other genetic variants likely contributed to woolly mammoth evolution. In this study, we sequenced two woolly mammoth genomes and ...

    • Integrating multi-taxon palaeogenomes and sedimentary ancient DNA to study past ecosystem dynamics 

      Dussex, Nicolas; Bergfeldt, Nora; de Anca Prado, Violeta; Dehasque, Marianne; Díez-del-Molino, David; Ersmark, Erik; Kanellidou, Foteini; Larsson, Petter; Lemež, Špela; Lord, Edana; Marmol-Sanchez, Emilio; Meleg, Ioana N.; Måsviken, Johannes; Naidoo, Thijessen; Studerus, Jovanka; Vicente, Mário; von Seth, Johanna; Götherström, Anders; Dalén, Love; Heintzman, Peter D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
      Ancient DNA (aDNA) has played a major role in our understanding of the past. Important advances in the sequencing and analysis of aDNA from a range of organisms have enabled a detailed understanding of processes such as past demography, introgression, domestication, adaptation and speciation. However, to date and with the notable exception of microbiomes and sediments, most aDNA studies have focused ...

    • Million-year-old DNA sheds light on the genomic history of mammoths 

      van der Valk, Tom; Pečnerová, Patrícia; Díez-del-Molino, David; Bergström, Anders; Oppenheimer, Jonas; Hartmann, Stefanie; Xenikoudakis, Georgios; Thomas, Jessica A.; Dehasque, Marianne; Sağlıcan, Ekin; Rabia Fidan, Fatma; Barnes, Ian; Liu, Shanlin; Somel, Mehmet; Heintzman, Peter D.; Nikolskiy, Pavel; Shapiro, Beth; Skoglund, Pontus; Hofreiter, Michael; Lister, Adrian M.; Götherström, Anders; Dalén, Love (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-17)
      Temporal genomic data hold great potential for studying evolutionary processes such as speciation. However, sampling across speciation events would, in many cases, require genomic time series that stretch well back into the Early Pleistocene subepoch. Although theoretical models suggest that DNA should survive on this timescale1, the oldest genomic data recovered so far are from a horse specimen ...

    • Pre-extinction demographic stability and genomic signatures of adaptation in the woolly rhinoceros 

      Lord, Edana; Dussex, Nicolas; Kierczak, Marcin; Díez-del-Molino, David; Ryder, Oliver A.; Stanton, David W. G.; Gilbert, Marcus Thomas Pius; Sánchez-Barreiro, Fatima; Zhang, Guojie; Sinding, Mikkel-Holger S.; Lorenzen, Eline D.; Willerslev, Eske; Protopov, Albert; Shidlovskiy, Fedor K.; Fedorov, Sergey; Bocherens, Hervé; Nathan, Senthilvel K.S.S.; Goossens, Benoit; van der Plicht, Johannes; Chan, Yvonne L.; Prost, Stefan; Potapova, Olga R; Kirillova, Irina V.; Lister, Adrian M.; Heintzman, Peter D.; Kapp, Joshua D.; Shapiro, Beth; Vartanyan, Sergey; Götherström, Anders; Dalén, Love (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-13)
      Ancient DNA has significantly improved our understanding of the evolution and population history of extinct megafauna. However, few studies have used complete ancient genomes to examine species responses to climate change prior to extinction. The woolly rhinoceros (<i>Coelodonta antiquitatis</i>) was a cold-adapted megaherbivore widely distributed across northern Eurasia during the Late Pleistocene ...